Asialoglycoprotein Receptor 1 anticorps (N-Term)
Aperçu rapide pour Asialoglycoprotein Receptor 1 anticorps (N-Term) (ABIN2798934)
Antigène
Voir toutes Asialoglycoprotein Receptor 1 (ASGR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30, N-Term
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Fonction
- Rabbit Anti-Human ASGR1 (N-term) Antibody
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Immunogène
- This ASGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000ASGR1 Antibody (N-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Asialoglycoprotein Receptor 1 (ASGR1)
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Autre désignation
- ASGR1
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Sujet
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Target Description: Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Gene Symbol: ASGR1
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Poids moléculaire
- 33186 Da
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ID gène
- 432
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UniProt
- P07306
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Pathways
- Thyroid Hormone Synthesis
Antigène
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